MILBETEL CAT WORMER 16/40 MILLIGRAMS BOX OF 2 BIOCANINA TABLETS

For cat.
Active vermifuge against roundworms and flatworms, acts in a single dose.
Small tablet, meat flavor.
From 2 Kilograms .
Product equivalent to Milbemax , Milbactor , Milprazikan and Milprazin.

Directions:
In cats over 2 kilograms:
Treatment of mixed infestations with immature and adult cestodes (tapeworms) and adult nematodes (roundworms) of the following species:

Cestodes:
Echinococcus multilocularis
Dipylidium caninum,
Taenia spp.,

Nematodes :
Ancylostoma tubaeforme,
Toxocara cati.

Usage tips :
Oral route.
In accordance with good veterinary practice, animals should be weighed to ensure accurate dosing.
Minimum recommended dose: 2 milligrams of milbemycin oxime and 5 milligrams of praziquantel per kilogram of body weight given as a single oral dose.
The product should be administered during or after the meal.
The product is a small tablet.
For ease of administration, the tablet is meat flavored (film coating).
Tablets can be split into two halves.

Depending on the weight of the cat, the dose to be administered is as follows:
Weight Tablets
2 to 4 kilograms = 1/2 tablet
4 to 8 kilograms = 1 tablet
8 to 12 kilograms = 1+1/2 tablets.

Properties :
Milbemycin oxime belongs to the group of macrocyclic lactones, produced by the fermentation of Streptomyces hygroscopicus var. aureolacrimosus. It is active against mites, the larval and adult stages of nematodes and the larvae of Dirofilaria immitis.
The activity of milbemycin is linked to its action on neurotransmission in invertebrates: milbemycin oxime, like avermectins and other milbemycins, increases membrane permeability to chloride ions in nematodes and insects via glutamate-dependent chloride channels ( related to GABAA and glycine receptors in vertebrates). This results in hyperpolarization of the neuromuscular membrane, flaccid paralysis and death of the parasite.

Praziquantel is an acetylated derivative of pyrazino-isoquinoline. Praziquantel is active against cestodes and trematodes. It modifies the membrane permeability to calcium (Ca2+ influx) in the parasite, which causes an imbalance of the membrane structures and leads to membrane depolarization, practically instantaneous muscle contractions (cramps) and rapid vacuolization of the integumentary syncytium, responsible decomposition of the integument (blisters). This facilitates elimination in the gastrointestinal tract or leads to the death of the parasite.

Composition :
One scored film-coated tablet contains:
Active substance(s):
Milbemycin oxime ……………16 milligrams.
Praziquantel ……………………… 40 milligrams.

Excipients:
Core
microcrystalline cellulose
Croscarmellose sodium
Magnesium Stearate
povidone
Anhydrous colloidal silica

Lamination:
Natural chicken liver flavor
Hypromellose
microcrystalline cellulose
Macrogol Stearate
Red Allura AC (E129)
Titanium dioxide (E171).

Contraindications:
Do not use in cats weighing less than 2 kilograms.
Do not use in case of hypersensitivity to the active substance(s) or to any of the excipients.

Side effects :
In very rare cases, and particularly in young cats, systemic symptoms (such as lethargy), neurological symptoms (such as muscle tremors
and ataxia) and/or gastrointestinal (such as vomiting and diarrhoea) may be observed after administration of the veterinary medicinal product.

Special Warnings:
* Special warnings for each target species:
It is recommended to treat all animals living in the same household at the same time.
It is recommended to seek the advice of a professional for the implementation of an effective worm control program, which takes into account the epidemiological context and the living conditions of the cat.
Parasite resistance to a particular class of anthelmintic may develop following frequent and repeated use of an anthelmintic of that class.
In the event of D. caninum infestation, concomitant treatment against intermediate hosts, such as fleas and lice, should be implemented to prevent re-infestation.

* Special precautions for use in animals:
No studies have been conducted in cats that are severely debilitated or have significant renal or hepatic impairment. The product is not recommended in these cases or only after evaluation of the risk/benefit ratio by the veterinarian.

The treatment of dogs with a large number of circulating microfilariae can sometimes give rise to the appearance of hypersensitivity reactions such as:
pale mucous membranes, vomiting, tremors, labored breathing or excessive salivation. These reactions are associated with the release of proteins from dead or dying microfilariae and are not a direct toxic effect of the product. Use in dogs with microfilaraemia is therefore not recommended.

In the absence of data in cats with microfilaraemia, the product should only be used after evaluation of the benefit/risk ratio by the veterinarian.

Echinococcosis poses a danger to human beings. In the event of echinococcosis, specific protocols for the treatment, follow-up and protection of persons must be followed. It is then advisable to consult an expert or a parasitology center. If the cat has been in an area where Echinococcus spp is very common, consult a
veterinary.

* Special precautions to be taken by the person administering the veterinary medicinal product to animals:
Wash hands after use. In case of accidental ingestion of tablets, especially by children, seek medical advice immediately and show the carton or package leaflet to the doctor .

* Use in case of pregnancy, lactation or laying:
In one study, this combination of active substances was shown to be well tolerated in breeding queens, including during pregnancy and lactation . As no specific study has been carried out with this product, the use of the product during pregnancy or lactation should be subject to a benefit/risk assessment by the veterinarian.

* Overdose:
A study was carried out with the product administered at 1 time, 3 times and 5 times the therapeutic dose, and over a period exceeding the therapeutic protocol, that is to say 3 administrations at 15-day intervals. Signs rarely reported at the recommended dose were observed at 5 times the therapeutic dose after the second and third treatment. These signs disappeared spontaneously after one day.

Our advice:
Puppy and kitten deworming schedule:
up to 2 months: twice a month
from 2 to 6 months: once a month
from 6 months: twice a year for indoor animals, 4 times a year for those with access to the outside and 6 times a year for animals in an echinococcosis zone.

Protecting your animal also means protecting its environment, but also its family and especially its children.

Do not forget to deworm a few days before any vaccination. Intestinal worms disrupt the immune system and alter the effectiveness of the vaccine.

After a deworming, it is possible that your animal is disturbed at the digestive level. This is often a sign that your pet was infested and is in the process of
to eliminate worms. We may recommend that you use an antiemetic before administering the dewormer.

Biocanina - 1 box of 2 scored tablets.

Veterinary use.